Regulation of autoimmune arthritis by the SHP-1 tyrosine phosphatase

The Src homology region 2 domain-containing phosphatase-1 (SHP-1) is known to exert negative regulatory effects on immune cell signaling. Mice with mutations in the Shp1 gene develop inflammatory skin disease and...

Source: Arthritis Research and Therapy - June 26, 2020 Category: Rheumatology Authors: Adrienn Markovics, Daniel M. Toth, Tibor T. Glant and Katalin Mikecz Tags: Research article Source Type: research