RHD genotyping of serological weak D phenotypes in the Iranian blood donors and patients

Most prevalent weak D types in the Caucasians molecularly defined weak D types 1, 2 or 3 and can be managed safely as RhD-positive, conserving limited supplies of RhD-negative RBCs. Therefore, identification of RHD alleles prevalence in each population could improve the policies related to accuracy of RhD typing. The aim of this study was to determine the frequency of RHD variant alleles among donors and patients for the first time in Iran.
Source: Transfusion and Apheresis Science - Category: Hematology Authors: Source Type: research