Presenilin 1 and APP Gene Mutations in Early-Onset AD Families from a Southeast Region of China.

CONCLUSION: The variant p. S290C (c.869-2＞G) in PSEN1 in the Chinese EOAD family revealed different clinical phenotypes when compared with that of Europeans.
PMID: 32579498 [PubMed - as supplied by publisher]

Source: Current Alzheimer Research - June 23, 2020 Category: Neurology Authors: Zhou J, Chen Y, Meng F, Zhang K, Liu X, Peng G Tags: Curr Alzheimer Res Source Type: research