Altered serum level of metabolic and endothelial factors in patients with systemic sclerosis

In conclusion, an increased serum level of resistin associated with increased endothelin-1 and fractalkine level and decreased adiponectin level may indicate a significant role of the adipose tissue in the development and progression of vascular abnormalities in patient s with systemic sclerosis. Fractalkine and galectin-3 may participate in promoting and exacerbating the fibrotic process in SSc.
Source: Archives of Dermatological Research - Category: Dermatology Source Type: research