Synthesis, Characterization, Anti-proliferative Evaluation, and DNA Flow Cytometry Analysis of Some 2-Thiohydantoin derivatives.

CONCLUSION: Insertion of pyrazole, oxadiazole and, quinazoline moieties with 2-thiohydantoin moiety led to the enhancement of its anti-proliferative activity. Hence they can be used as anticancer agents.
PMID: 32525773 [PubMed - as supplied by publisher]

Source: Mini Reviews in Medicinal Chemistry - June 9, 2020 Category: Chemistry Authors: Elhady HA, Al-Shareef HF Tags: Mini Rev Med Chem Source Type: research