Clinical trial to evaluate the therapeutic benefits of limbal-supported contact lens wear for ocular sequelae due to Stevens-Johnson syndrome/toxic epidermal necrolysis

Stevens-Johnson syndrome (SJS), and its more severe variant, toxic epidermal necrolysis (TEN), are acute inflammatory disorders of the skin and mucous membranes that can result in life-threatening complications such as sepsis, respiratory dysfunction, and multiple organ failure [1 –4]. Although the incidence rate of SJS/TEN is very low, both disorders can affect anyone, regardless of age, usually as a consequence of adverse drug reactions. In 77% of SJS/TEN patients, ocular complications are involved at the acute stage of the disease [5].

Source: Contact Lens and Anterior Eye - June 4, 2020 Category: Opthalmology Authors: Motohiro Itoi, Mayumi Ueta, Ken Ogino, Eriko Sumi, Kojiro Imai, Satoshi Teramukai, Shigeru Kinoshita, Chie Sotozono Source Type: research