Evolving role of microRNAs in uterine fibroid pathogenesis: filling the gap!
Uterine fibroids (leiomyoma) are benign monoclonal neoplasms of the myometrium and represent the most common tumors in women worldwide. Tumors occur in ∼77% of women overall and are clinically manifest in ∼25% by age 45 years. Although benign, these tumors are nonetheless associated with significant morbidity; they are the primary indication for hysterectomy, and a major source of gynecologic and reproductive dysfunction, ranging from profuse m enstrual bleeding and pelvic pain to infertility, recurrent miscarriage, and preterm labor.
Source: Fertility and Sterility - Category: Reproduction Medicine Authors: Mohamed Ali, Sahar Esfandyari, Ayman Al-Hendy Tags: Reflections Source Type: research
More News: Bleeding | Hysterectomy | Infertility | Leiomyoma | Miscarriage | Pain | Reproduction Medicine | Women