Endogenous levels of 1-O-acylceramides increase upon acidic ceramidase deficiency and decrease due to loss of Dgat1 in a tissue-dependent manner

Publication date: Available online 28 May 2020Source: Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of LipidsAuthor(s): Aline Bayerle, Christian Marsching, Mariona Rabionet, Shaalee Dworski, Mustafa A. Kamani, Chandramohan Chitraju, Nina L. Gluchowski, Katlyn R. Gabriel, Silke Herzer, Richard Jennemann, Thierry Levade, Jeffrey A. Medin, Roger Sandhoff
Source: Biochimica et Biophysica Acta (BBA) Molecular and Cell Biology of Lipids - Category: Lipidology Source Type: research

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Publication date: Available online 14 July 2020Source: British Journal of Oral and Maxillofacial SurgeryAuthor(s): L. Khojastepour, M. Moannaei, H.R. Eftekharian, M.S. Khaghaninejad, M. Mahjoori-Ghasrodashti, S. Tavanafar
Source: British Journal of Oral and Maxillofacial Surgery - Category: ENT & OMF Source Type: research
Publication date: Available online 15 July 2020Source: Diabetes &Metabolic Syndrome: Clinical Research &ReviewsAuthor(s): M.G. Rajanandh
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - Category: Endocrinology Source Type: research
Publication date: Available online 13 July 2020Source: Canadian Journal of DiabetesAuthor(s): Yiting Wang, Fang Liu
Source: Canadian Journal of Diabetes - Category: Endocrinology Source Type: research
Conclusion: This is the first study that reported the altered expression of exosomal miR-34a among children and adolescents with T1DM. Moreover, association of miR-34a with markers of dyslipidemia and endothelial dysfunction was identified, suggesting that it could play a role in regulation of lipid metabolism and endothelial function in T1DM. PMID: 32654473 [PubMed - as supplied by publisher]
Source: JCRPE Journal of Clinical Research in Pediatric Endocrinology - Category: Endocrinology Tags: J Clin Res Pediatr Endocrinol Source Type: research
Authors: Dourado M, Cavalcanti F, Vilar L, Cantilino A Abstract CKD has a high prevalence worldwide, mainly due to its main etiologies-diabetes and hypertension. It has high cardiovascular morbidity and mortality, with traditional risk factors such as atherosclerosis, hypertension, diabetes, smoking, and left ventricular hypertrophy being common. Nontraditional cardiovascular risk factors, such as anemia, hyperparathyroidism, chronic inflammation, and microalbuminuria, are also well studied. Prolactin is a hormone not only related to lactation but also being considered a uremic toxin by some authors. It accumulates...
Source: International Journal of Endocrinology - Category: Endocrinology Tags: Int J Endocrinol Source Type: research
Erratum to "Gastroenteropancreatic Neuroendocrine Neoplasia Characterization in Portugal: Results from the NETs Study Group of the Portuguese Society of Endocrinology, Diabetes and Metabolism". Int J Endocrinol. 2020;2020:9184324 Authors: Santos AP, Vinagre J, Soares P, Claro I, Sanches AC, Gomes L, Fernandes I, Catarino AL, Preto J, Pereira BD, Marques AP, Rodrigues F, Amaral C, Rocha G, Mellidez JC, Simões H, Lopes JM, Bugalho MJ, On Behalf Of The NETs Study Group Of The Portuguese Society Of Endocrinology Diabetes And Metabolism Abstract [This corrects the article DOI: 10.1155/2019/...
Source: International Journal of Endocrinology - Category: Endocrinology Tags: Int J Endocrinol Source Type: research
Conclusions: Maternal serum TG/HDL levels at late gestation are positively associated with neonatal body weight and the risk of macrosomia in women without DM. Maintaining maternal lipid levels in an appropriate range is important in the context of fetal overgrowth and primary prevention of macrosomia. PMID: 32655633 [PubMed]
Source: International Journal of Endocrinology - Category: Endocrinology Tags: Int J Endocrinol Source Type: research
Authors: Sun Z, Li P, Wang X, Lai S, Qiu H, Chen Z, Hu S, Yao J, Shen J Abstract As the major cause of female anovulatory infertility, polycystic ovary syndrome (PCOS) affects a great proportion of women at childbearing age. Although glucagon-like peptide 1 receptor agonists (GLP-IRAs) show therapeutic effects for PCOS, its target and underlying mechanism remains elusive. In the present study, we identified that, both in vivo and in vitro, GLP-1 functioned as the regulator of proliferation and antiapoptosis of MGCs of follicle in PCOS mouse ovary. Furthermore, forkhead box protein O1 (FoxO1) plays an important role...
Source: International Journal of Endocrinology - Category: Endocrinology Tags: Int J Endocrinol Source Type: research
Publication date: Available online 14 July 2020Source: Seminars in Cancer BiologyAuthor(s): Rui Caetano Oliveira, Henrique Alexandrino, Maria Augusta Cipriano, Filipe Caseiro Alves, José Guilherme Tralhão
Source: Seminars in Cancer Biology - Category: Cancer & Oncology Source Type: research
Publication date: Available online 13 July 2020Source: Journal of Bone OncologyAuthor(s): Xiaomeng Li, Ning Wu, Wenjie Zhang, Ying Liu, Yue Ming
Source: Journal of Bone Oncology - Category: Cancer & Oncology Source Type: research
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