The role of sodium channels in sudden unexpected death in pediatrics

ConclusionWe report variants in several VGSC genes in cases with SUDP, involving both arrhythmia ‐ and epilepsy‐associated genes. Accurate variant assessment as well as future studies are essential for an improved understanding of the contribution of sodium channel‐related variants to SUDP.

Source: Molecular Genetics & Genomic Medicine - May 24, 2020 Category: Genetics & Stem Cells Authors: Anne M. Rochtus, Richard D. Goldstein, Ingrid A. Holm, Catherine A. Brownstein, Eduardo P érez‐Palma, Robin Haynes, Dennis Lal, Annapurna H. Poduri Tags: ORIGINAL ARTICLE Source Type: research