Inhibition of neutrophil inflammatory mediator expression by azithromycin

ConclusionAZM is a consistent and effective inhibitor of neutrophil inflammatory mediator mRNA expression.Clinical relevanceGiven that a single dose of AZM produces higher and more sustained concentrations of this agent in periodontal tissues than AMX when used as a pre-operative prophylactic antibiotic, AZM has greater potential to inhibit inflammatory mediator expression at peri-implant wound sites than AMX.

http://link.springer.com/10.1007/s00784-020-03314-4

Source: Clinical Oral Investigations - May 20, 2020 Category: Dentistry Source Type: research