Study indicates the need to revise the protocol for detecting Zika in placenta

(Funda ç ã o de Amparo à Pesquisa do Estado de S ã o Paulo) Brazilian researchers show that the virus can infect different placental regions and that collection and storage methods should be taken into consideration to ensure that the results are trustworthy and representative.
Source: EurekAlert! - Infectious and Emerging Diseases - Category: Infectious Diseases Source Type: news

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Publication date: Available online 31 May 2020Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral RadiologyAuthor(s): Ana Márcia Menezes de Oliveira, Elisama Gomes Magalhães de Melo, Mário Luis Tavares Mendes, Sheila Jaqueline Gomes dos Santos Oliveira, Carolina Santos Souza Tavares, Andreia Centenaro Vaez, Sara Juliana Abreu de Vasconcelos, Hudson P. Santos, Victor Santana Santos, Paulo Ricardo Saquete Martins-Filho
Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology - Category: ENT & OMF Source Type: research
Elevated levels of a neurotoxin in northeastern Brazil's drinking water and a high incidence of microcephaly in the region led scientists to look for a link, and they found one.
Source: The Scientist - Category: Science Tags: Notebook Magazine Issue Source Type: news
The zika fever is a self-limiting disease caused by the Zika virus (ZIKV) infection, which is transmitted by Aedes aegypti (Weaver et al. 2016). As the first reported epidemics happened in African and Asian continents, ZIKV is classically classified in three lineages: East African, West African, and Asian. Moreover, the Asian lineage is further classified by geographical origin as Micronesian, Cambodian and Malaysian (Haddow et al., 2012). The strains isolated during the outbreak in Brazil were classified as Asian lineage (Faria et al.
Source: International Journal of Infectious Diseases - Category: Infectious Diseases Authors: Tags: Short Communication Source Type: research
The aim of this study was to investigate oral and maxillofacial outcomes in children with congenital Zika syndrome (CZS) and the presence of nonnutritive sucking habits, functional habits, and features related to breastfeeding and nutrition of these children.
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - Category: ENT & OMF Authors: Tags: Original Article Source Type: research
Publication date: Available online 29 May 2020Source: Neurología (English Edition)Author(s): L. del Carpio Orantes
Source: Neurologia - Category: Neurology Source Type: research
Gil Oliva Single-stranded positive RNA ((+) ssRNA) viruses include several important human pathogens. Some members are responsible for large outbreaks, such as Zika virus, West Nile virus, SARS-CoV, and SARS-CoV-2, while others are endemic, causing an enormous global health burden. Since vaccines or specific treatments are not available for most viral infections, the discovery of direct-acting antivirals (DAA) is an urgent need. Still, the low-throughput nature of and biosafety concerns related to traditional antiviral assays hinders the discovery of new inhibitors. With the advances of reverse genetics, reporter re...
Source: Viruses - Category: Virology Authors: Tags: Review Source Type: research
Discussions with the FDA are ongoing to define the required data set for filing Janssen’s Ebola vaccine regimen under the FDA’s Animal Rule licensure pathway. About Janssen’s Ebola Vaccine Regimen The Janssen investigational preventive Ebola vaccine regimen (Ad26.ZEBOV, MVA-BN-Filo) utilizes a viral vector strategy in which viruses – in this case adenovirus serotype 26 (Ad26) and Modified Vaccinia Virus Ankara (MVA) – are genetically modified so that they cannot replicate in human cells. In addition, these vectors are modified to safely carry the genetic code of an Ebola virus protein in order...
Source: Johnson and Johnson - Category: Pharmaceuticals Tags: Innovation Source Type: news
Publication date: Available online 28 May 2020Source: Neurología (English Edition)Author(s): S. Yasri, V. Wiwanitkit
Source: Neurologia - Category: Neurology Source Type: research
While existing studies have investigated the role of social media on health-related communication, little is known about the potential differences between different users groups on different social media platf...
Source: BMC Public Health - Category: Consumer Health News Authors: Tags: Research article Source Type: research
Abstract The emergence and re-emergence of Zika virus (ZIKV), is a cause for international concern. These highly pathogenic arboviruses represent a serious health burden in tropical and subtropical areas worldwide. Despite these burdens, antiviral therapies do not exist, and inhibitors of ZIKV are therefore urgently needed. To elucidate the anti-ZIKV effect of lycorine, we used reverse transcription-quantitative real-time PCR (qRT-PCR), immunofluorescence, Westernwestern blot, and plaque forming assay to analyse viral RNA (vRNA), viral protein, progeny virus counts, and validated inhibitors in vitro using a variet...
Source: Virology - Category: Virology Authors: Tags: Virology Source Type: research
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