Precision toxicity correlates of tumor spatial proximity to organs at risk in cancer patients receiving intensity-modulated radiotherapy.
CONCLUSION: Our results show that spatial information available pre-treatment can be used to robustly identify groups of RAD high-risk patients. We identify feature sets that considerably improve toxicity risk prediction beyond what is possible using baseline features. Our results also suggest that similarity-based predicted mean doses to organs can be used as valid predictors of risk to organs.
PMID: 32422303 [PubMed - as supplied by publisher]
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - Category: Radiology Authors: Wentzel A, Hanula P, van Dijk LV, Elgohari B, S R Mohamed A, Cardenas CE, Fuller CD, Vock DM, Canahuate G, Elisabeta Marai G Tags: Radiother Oncol Source Type: research
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