Effect of ageing on tactile transduction processes.

Effect of ageing on tactile transduction processes.
Ageing Res Rev. 2013 Dec 26;
Authors: Decorps J, Saumet JL, Sommer P, Sigaudo-Roussel D, Fromy B
Abstract
With advancing age, a decline in the main sensory modalities including touch sensation and perception is well reported to occur. This review mainly outlines the peripheral components of touch perception highlighting ageing influences on morphological and functional features of cutaneous mechanical transducers and mechanosensitive ion channels, sensory innervation, neurotransmitters and even vascular system required to ensure efferent function of the afferent nerve fibres in the skin. This, in conjunction with effect of ageing on the skin per se and central nervous system, could explain the tactile deficit seen among the ageing population. We also discuss appropriate tools and experimental models available to study the age-related tactile decline.
PMID: 24373814 [PubMed - as supplied by publisher]

Source: Ageing Research Reviews - December 26, 2013 Category: Genetics & Stem Cells Authors: Decorps J, Saumet JL, Sommer P, Sigaudo-Roussel D, Fromy B Tags: Ageing Res Rev Source Type: research