Dominant gut Prevotella copri in gastrectomised non-obese diabetic Goto –Kakizaki rats improves glucose homeostasis through enhanced FXR signalling

ConclusionsOur data underline the impact of intestinalP. copri on improved glucose homeostasis through enhanced bile acid metabolism and farnesoid X receptor (FXR) signalling, which may represent a promising opportunity for novel type 2 diabetes therapeutics.

Source: Diabetologia - May 15, 2020 Category: Endocrinology Source Type: research