Chemical profile of the parotoid gland secretion of the Amazonian toad (Rhinella margaritifera).

Chemical profile of the parotoid gland secretion of the Amazonian toad (Rhinella margaritifera).
Toxicon. 2020 May 05;:
Authors: Sinhorin AP, Kerkhoff J, Dall Oglio EL, de Jesus Rodrigues D, de Vasconcelos LG, Sinhorin VDG
Abstract
The secreted poisonin bufonids (Anura: Bufonidae) include proteins, biogenic amines, toxic bufadienolides and alkaloids. The chemical composition of the methanolic extract of parotoid gland secretions by the Amazonian toad Rhinella margaritifera was evaluated in a UFLC-DAD-micrOTOF system. Of the twenty three compounds found in the methanolic extract, eighteen were identified by the mass/charge ratio as: five arginine diacids, six bufagenins (telocinobufagin, marinobufagin, bufotalin, cinobufotalin, bufalin and cinobufagin), six bufotoxins, and an alkaloid (dehydrobufotenin).
PMID: 32387184 [PubMed - as supplied by publisher]

Source: Toxicon - May 4, 2020 Category: Toxicology Authors: Sinhorin AP, Kerkhoff J, Dall Oglio EL, de Jesus Rodrigues D, de Vasconcelos LG, Sinhorin VDG Tags: Toxicon Source Type: research