Using the exposome to address gene–environment interactions in kidney disease

Nature Reviews Nephrology, Published online: 11 May 2020; doi:10.1038/s41581-020-0302-9New exposome-based approaches permit omic-scale characterization of the non-genetic contributors to kidney disease. High-resolution mass spectrometry analysis of plasma and urine samples captures a wide range of exogenous and endogenous metabolites that can be used in combination with genetic risk factors to identify new biomarkers of exposure and therapeutic approaches.
Source: Nature Reviews Nephrology - Category: Urology & Nephrology Authors: Source Type: research