Development of embryonic and adult leukemia mouse models driven by MLL-ENL translocation

The myeloid-lymphoid or mixed lineage leukemia gene (MLL/kmt2a) has a major contribution to aggressive acute leukemias in the 85% of infant (18 yrs old) (Sam et al., 2012; Winters and Bernt, 2017).

Source: Experimental Hematology - May 9, 2020 Category: Hematology Authors: Roshani Sinha, Cristina Porcheri, Teresa d'Altri, Jessica Gonz ález, Cristina Ruiz Herguido, Terry Rabbits, Lluis Espinosa, Anna Bigas Salvans Tags: Brief Communication Source Type: research