Serum Levels of Alpha Fetoprotein Increased More Than 10 Years Before Detection of Hepatocellular Carcinoma.

Ultrasound (US)-based screening has been recommended for patients with an increased risk of hepatocellular Carcinoma (HCC). US analysis is, however, limited in patients who are obese or have small tumors. Addition of measurement of serum level of alpha-fetoprotein (AFP) to US analysis can increase detection of HCC. We analyzed data from patients with chronic liver disease, collected over 15 years in an HCC surveillance program, to develop a model to assess risk of HCC.
Source: Clinical Gastroenterology and Hepatology - Category: Gastroenterology Authors: Source Type: research