Correlation between serological biomarkers of extracellular matrix turnover and lung fibrosis and pulmonary artery hypertension in patients with systemic sclerosis

ConclusionOur study indicated that collagen turnover abnormality, especially type VI collagen, is not only important pathologically in skin sclerosis but also in organ involvement. These biomarkers of collagen turnover are potentially clinically useful as biomarkers of organ involvement in SSc.

Source: International Journal of Rheumatic Diseases - April 13, 2020 Category: Rheumatology Authors: Satoshi Kubo, Anne Sofie Siebuhr, Anne ‐C. Bay‐Jensen, Pernille Juhl, Morten A. Karsdal, Yurie Satoh, Yasuyuki Todoroki, Kazuhisa Nakano, Shingo Nakayamada, Yoshiya Tanaka Tags: ORIGINAL ARTICLE Source Type: research