Impact of β-Blockers on Heart Rate and Oxygen Uptake During Exercise and Recovery in Older Patients With Heart Failure With Preserved Ejection Fraction
Purpose:
The study aimed to investigate the differences in oxygen uptake (
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O2) and heart rate (HR) (at rest, submaximal exercise, peak exercise, and recovery) in patients with heart failure with preserved ejection fraction (HFpEF) with β-blockers (BB) or without BB treatment (NBB) and to analyze the relationship between HR reserve (HRresv) and peak
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O2 (
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O2peak) in BB and NBB.
Methods:
A total of 174 HFpEF patients (>65 yr; BB, n = 59; NBB, n = 115) were assessed with a cardiopulmonary exercise test to peak exertion using an incremental protocol. After 5 min of supine rest, HR and
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O2 (HRrest,
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O2rest) at submaximal exercise (HRsubmax,
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O2submax), at peak exercise (HRpeak,
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O2peak), at 1 min of passive recovery (HRrec1), HRresv (HRpeak− HRrest), and HR recovery (HRrecov = HRpeak− HRrec1) were evaluated.
Results:
Analysis showed that HRrest (66.0...
Source: Journal of Cardiopulmonary Rehabilitation - Category: Rehabilitation Tags: Cardiac Rehabilitation Source Type: research