Impact of β-Blockers on Heart Rate and Oxygen Uptake During Exercise and Recovery in Older Patients With Heart Failure With Preserved Ejection Fraction

Purpose: The study aimed to investigate the differences in oxygen uptake ( JOURNAL/jcprh/04.02/01273116-202005000-00007/math_7MM1/v/2020-04-30T103411Z/r/image-png O2) and heart rate (HR) (at rest, submaximal exercise, peak exercise, and recovery) in patients with heart failure with preserved ejection fraction (HFpEF) with β-blockers (BB) or without BB treatment (NBB) and to analyze the relationship between HR reserve (HRresv) and peak JOURNAL/jcprh/04.02/01273116-202005000-00007/math_7MM2/v/2020-04-30T103411Z/r/image-png O2 ( JOURNAL/jcprh/04.02/01273116-202005000-00007/math_7MM3/v/2020-04-30T103411Z/r/image-png O2peak) in BB and NBB. Methods: A total of 174 HFpEF patients (>65 yr; BB, n = 59; NBB, n = 115) were assessed with a cardiopulmonary exercise test to peak exertion using an incremental protocol. After 5 min of supine rest, HR and JOURNAL/jcprh/04.02/01273116-202005000-00007/math_7MM4/v/2020-04-30T103411Z/r/image-png O2 (HRrest, JOURNAL/jcprh/04.02/01273116-202005000-00007/math_7MM5/v/2020-04-30T103411Z/r/image-png O2rest) at submaximal exercise (HRsubmax, JOURNAL/jcprh/04.02/01273116-202005000-00007/math_7MM6/v/2020-04-30T103411Z/r/image-png O2submax), at peak exercise (HRpeak, JOURNAL/jcprh/04.02/01273116-202005000-00007/math_7MM7/v/2020-04-30T103411Z/r/image-png O2peak), at 1 min of passive recovery (HRrec1), HRresv (HRpeak− HRrest), and HR recovery (HRrecov = HRpeak− HRrec1) were evaluated. Results: Analysis showed that HRrest (66.0...
Source: Journal of Cardiopulmonary Rehabilitation - Category: Rehabilitation Tags: Cardiac Rehabilitation Source Type: research