HER2 overexpression as a poor prognostic determinant in resected biliary tract cancer.

CONCLUSION: HER2 overexpression represents an independent prognostic factor for disease recurrence in BTC treated with potentially curative surgery. IMPLICATIONS FOR PRACTICE: HER2 overexpression may play an independent role in promoting an aggressive behavior in resectable biliary tract cancer. This evidence could be helpful in improving prognostic stratification after resection and, primarily, should endorse the rationale to investigate HER2 as a therapeutic target in BTC. PMID: 32353192 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32353192?dopt=Abstract

Source: The Oncologist - April 29, 2020 Category: Cancer & Oncology Authors: Vivaldi C, Fornaro L, Ugolini C, Niccoli C, Musettini G, Pecora I, Cacciato Insilla A, Salani F, Pasquini G, Catanese S, Lencioni M, Masi G, Campani D, Fontantini G, Falcone A, Vasile E Tags: Oncologist Source Type: research