Predicting final lesion characteristics during MR-guided focused ultrasound pallidotomy for treatment of Parkinson's disease.

CONCLUSIONS: The authors' acoustic simulations accurately depicted the characteristics of thermal lesions encountered following MRgFUS pallidotomy. MR thermometry data can predict postprocedure day 1 GPi lesion characteristics using a 48°C threshold model. Finally, the lower treatment efficiency of pallidotomy may make GPi lesioning challenging in patients with a low SDR.
PMID: 32330882 [PubMed - as supplied by publisher]

Source: Journal of Neurosurgery - April 23, 2020 Category: Neurosurgery Authors: Miller TR, Guo S, Melhem ER, Eisenberg HM, Zhuo J, Kelm N, Dayan M, Gullapalli RP, Gandhi D Tags: J Neurosurg Source Type: research