Gli2 mediates the development of castration ‑resistant prostate cancer.

In conclusion, to the best of our knowledge, the present study was the first occasion in which the essential role of Gli2 in the development of CRPC was demonstrated, providing a potential therapeutic target for the intervention of CRPC. PMID: 32319599 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32319599?dopt=Abstract

Source: International Journal of Oncology - April 12, 2020 Category: Cancer & Oncology Authors: Xia L, Bouamar H, Gu X, Zeballos C, Qin T, Wang B, Zhou Y, Wang Y, Yang J, Zhu H, Zhang W, Houghton PJ, Sun LZ Tags: Int J Oncol Source Type: research