Cobalt oxyhydroxide nanoflakes with oxidase-mimicking activity induced chemiluminescence of luminol for glutathione detection.

Cobalt oxyhydroxide nanoflakes with oxidase-mimicking activity induced chemiluminescence of luminol for glutathione detection. Talanta. 2020 Aug 01;215:120928 Authors: Yang XJ, Li RS, Li CM, Li YF, Huang CZ Abstract Cobalt oxyhydroxide nanoflakes (CoOOH NFs), a typical two-dimensional (2D) nanomaterials, were found to induce chemiluminescence (CL) of luminol since the oxidase-like activity of CoOOH NFs enables the dissolved oxygen to generate various radicals (OH, O2-and 1O2) even if without the addition of oxidants such as hydrogen peroxide, and these radicals could be scavenged by glutathione (GSH), making GSH could be detected sensitively in the range of 10 nM to 1 μM with the detection limit of 6.4 nM. PMID: 32312465 [PubMed]
Source: Talanta - Category: Chemistry Authors: Tags: Talanta Source Type: research