ILC3s: Rhythmic Keepers of Gut Integrity at Mealtime.

ILC3s: Rhythmic Keepers of Gut Integrity at Mealtime.
Trends Immunol. 2020 Apr 16;:
Authors: Quatrini L, Moretta L, Mingari MC
Abstract
Cyclically, during the day, increased permeability of the intestinal epithelial barrier, allowing nutrient uptake, must be compensated for, to achieve increased protection against potentially harmful components. Seillet et al. demonstrate that, upon food intake, enteric neuron-derived VIP promotes anticipatory mucosal immunity by inducing ILC3s to produce protective IL-22.
PMID: 32307240 [PubMed - as supplied by publisher]

Source: Trends in Immunology - April 15, 2020 Category: Allergy & Immunology Authors: Quatrini L, Moretta L, Mingari MC Tags: Trends Immunol Source Type: research