[Retroperitoneal lymph node assessment in pediatric paratesticular rhabdomyosarcoma].

[Retroperitoneal lymph node assessment in pediatric paratesticular rhabdomyosarcoma].
Bull Cancer. 2020 Apr 14;:
Authors: Guérin F, Martelli H
Abstract
Paratesticular Rhabdomyosarcoma accounts for 7 to 11% of pediatric rhabdomyosarcomas. Children older than 10 years have a worse event-free survival (69 to 80% vs. 87 to 92%) than children younger than 10 years. In this location, the relapses are essentially in the retroperitoneal lymph nodes and are often fatal. In European protocols, the assessment of the retroperitoneal lymph nodes at diagnosis is made by imaging whereas it is performed by retroperitoneal lymph node dissection in the American protocols. This method has been proved to improve event-free survival in the group of patient older than 10 years with a tumour bigger than 5cm. In the next European protocol, when nodes will be enlarged a surgical biopsy will be performed, this will be irrespective of age or size, and when no nodes will be enlarged in patients older than 10 years, retroperitoneal lymph node assessment will be performed. Other techniques of lymph nodes assessment will be tested like sentinel node biopsies or PET-scan.
PMID: 32303361 [PubMed - as supplied by publisher]

Source: Bulletin du Cancer - April 13, 2020 Category: Cancer & Oncology Authors: Guérin F, Martelli H Tags: Bull Cancer Source Type: research