Perceptions of Clinical Trial Participation Among Women of Varying Health Literacy Levels.

Perceptions of Clinical Trial Participation Among Women of Varying Health Literacy Levels. Oncol Nurs Forum. 2020 May 01;47(3):273-280 Authors: Burks AC, Doede A, Showalter SL, Keim-Malpass J Abstract PURPOSE: To understand the perceptions of risk, benefit, and the informed consent process after enrolling in and completing a phase 2 clinical trial using intraoperative radiation therapy (IORT) for early-stage breast cancer, and to determine how perceptions varied based on women's health literacy levels. PARTICIPANTS & SETTING: 20 participants who had already completed a phase 2 IORT clinical trial for early-stage breast cancer at an academic medical center. METHODOLOGIC APPROACH: A qualitative descriptive study was conducted using structured interviews consisting of questions aimed to elicit responses from participants regarding experiences of informed consent and the research process. A validated brief health literacy questionnaire was used to determine health literacy levels of participants. The authors analyzed themes using inductive thematic analysis. FINDINGS: Women with lower levels of health literacy reported feeling confident enough in the provider to make the decision to enroll in the clinical trial during the initial consultation, and, in general, women reported relying heavily on provider recommendation for enrolling in the clinical trial. IMPLICATIONS FOR NURSING: Tailored approaches...
Source: Oncology Nursing Forum - Category: Nursing Authors: Tags: Oncol Nurs Forum Source Type: research