Osteoporosis-decreased extracellular matrix stiffness impairs connexin 43-mediated gap junction intercellular communication in osteocytes.
This study demonstrates the correlation between ECM mechanical property and cell-to-cell communication in osteocytes and might pave the way for further exploration of osteoporosis in terms of biomechanics.
PMID: 32286624 [PubMed - as supplied by publisher]
Source: Acta Biochimica et Biophysica Sinica - Category: Biochemistry Authors: Zhang D, Li X, Pi C, Cai L, Liu Y, Du W, Yang W, Xie J Tags: Acta Biochim Biophys Sin (Shanghai) Source Type: research