Alanine, arginine, cysteine, and proline but not glutamine are substrates for and acute mediators of the liver-alpha cell axis in female mice.

CONCLUSION: Our data suggest that alanine, arginine, cysteine, and proline but not glutamine are involved in the acute regulation of the liver-alpha cell axis in female mice as they all increased glucagon secretion and their disappearance rate was altered by GRA.
PMID: 32255678 [PubMed - as supplied by publisher]

Source: Am J Physiol Endocri... - April 6, 2020 Category: Endocrinology Authors: Galsgaard KD, Jepsen SL, Kjeldsen SAS, Pedersen J, Wewer Albrechtsen NJ, Holst JJ Tags: Am J Physiol Endocrinol Metab Source Type: research