Clinical Trial for Severely Ill COVID-19 Patients Now Underway at Montefiore-Einstein

(BRONX, NY)—April 3, 2020—Montefiore Health System andAlbert Einstein College of Medicine has started treating very sick COVID-19 patients as part of a multicenter trial evaluating a potential therapy for the new disease. The double-blind, placebo-controlled trial is testing whether sarilumab, a drug already approved for treating rheumatoid arthritis, can halt the inflammation that can overwhelm the lungs of COVID-19 patients. A very similar drug yielded promising results in a recent study involving patients in China.
Source: Einstein News - Category: Universities & Medical Training Source Type: news

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Source: Healthcare News - Category: Pharmaceuticals Authors: Tags: Science /science Innovation /innovation Healthcare /healthcare Editors' Pick editors-pick Coronavirus technology alexknappblog Source Type: news
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Source: Molecular and Cellular Biochemistry - Category: Biochemistry Authors: Tags: Mol Cell Biochem Source Type: research
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Source: Autoimmunity Highlights - Category: Allergy & Immunology Source Type: research
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Source: The University of Arizona: Health - Category: Universities & Medical Training Authors: Source Type: research
Nature Reviews Rheumatology, Published online: 30 September 2020; doi:10.1038/s41584-020-00521-xCardiac toxicity can be induced by hydroxychloroquine, especially when used in combination with azithromycin. Interest in hydroxychloroquine and azithromycin as potential therapies for COVID-19 has renewed concerns about the possible cardiovascular risk these drugs present to patients with rheumatoid arthritis.
Source: Nature Reviews Rheumatology - Category: Rheumatology Authors: Source Type: research
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Source: The Economic Times - Category: Consumer Health News Source Type: news
ConclusionCoping with the COVID-19 pandemic was associated with rheumatic disease –related physical and psychological effects, even among patients not infected with SARS-CoV-2. According to patients, these effects adversely impacted their rheumatic diseases. Clinicians will need to ascertain the long-term sequelae of these effects and determine what therapeutic and psychologica l interventions are indicated.
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