Brief Summary of Potential SARS-CoV-2 Prophylactic and Treatment Drugs in the Emergency Department

We present a brief overview of the potential prophylactic and treatment agents under investigation, some which could be initiated in the ED if proven effective.
Source: Western Journal of Emergency Medicine - Category: Emergency Medicine Source Type: research

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Conclusion Medical device specialists want to help, but responding to pandemic shortages can be complicated. These takeaways come from our experience with building PPE, but they apply to any collaborative rapid response project. Use these tips as a framework to get you and your team on the path to meaningful progress.
Source: MDDI - Category: Medical Devices Authors: Tags: Design Source Type: news
Paul Offit, MD, of the Children's Hospital of Philadelphia, discusses principles and progress to date in COVID-19 vaccine development. Recorded June 1, 2020. Related: Adverse Consequences of Rushing a SARS-CoV-2 Vaccine: Implications for Public Trust
Source: JAMA Author Interviews - Category: General Medicine Authors: Source Type: podcasts
Emmie de Wit joins TWiV to explain her work on the pathogenesis of infection with SARS-CoV-2 in rhesus macaques, including studies on remdesivir and a vaccine candidate. Click arrow to playDownload TWiV 622 (41 MB .mp3, 68 min)Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv
Source: virology blog - Category: Virology Authors: Tags: Uncategorized ChAdOX vaccine candidate COVID-19 nonhuman primate remdesivir rhesus macaque SARS-CoV-2 viral virology virus viruses Source Type: blogs
Vidya M Mahalmani, Dhruv Mahendru, Ankita Semwal, Sukhmeet Kaur, Harpinder Kaur, Phulen Sarma, Ajay Prakash, Bikash MedhiIndian Journal of Pharmacology 2020 52(2):117-129 In December 2019, severe acute respiratory syndrome-coronavirus-2, a novel coronavirus, initiated an outbreak of pneumonia from Wuhan in China, which rapidly spread worldwide. The clinical characteristics of the disease range from asymptomatic cases or mild symptoms, which include nonspecific symptoms such as fever, cough, sore throat, headache, and nasal congestion to severe cases such as pneumonia, respiratory failure demanding mechanical ventilation t...
Source: Indian Journal of Pharmacology - Category: Drugs & Pharmacology Authors: Source Type: research
The objective of this article is to review and discuss the possible role of these drugs in the therapy of COVID-19.
Source: Clinical Rheumatology - Category: Rheumatology Source Type: research
Our “hidden enemy,” in plain sight.
Source: NYT Health - Category: Consumer Health News Authors: Tags: your-feed-science SARS (Severe Acute Respiratory Syndrome) Coronavirus (2019-nCoV) Research Proteins Microbiology Immune System Vaccination and Immunization RNA (Ribonucleic Acid) Biology and Biochemistry your-feed-health Nature Medi Source Type: news
Condition:   COVID-19 Interventions:   Biological: Low dosage Inactivated SARS-CoV-2 Vaccine on a 0- and 28-day schedule;   Biological: Low dosage Inactivated SARS-CoV-2 Vaccine on a 0- and 14-day schedule;   Biological: Medium dosage Inactivated SARS-CoV-2 Vaccine on a 0- and 28-day schedule;   Biological: Medium dosage Inactivat ed SARS-CoV-2 Vaccine on a 0- and 14-day schedule;   Biological: High dosage Inactivated SARS-CoV-2 Vaccine on a 0- and 28-day schedule;   Biological: High dosage Inactivated SARS-CoV-2 Vaccine on a 0- and 14-day schedule;   Biological: Placebo on...
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Emmie de Wit joins TWiV to explain her work on the pathogenesis of infection with SARS-CoV-2 in rhesus macaques, including studies on remdesivir and vaccine candidate. Hosts: Vincent Racaniello, Rich Condit, and Brianne Barker Guest: Emmie de Wit Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Respiratory disease in macaques inoculated with SARS-CoV-2 (Nature) Clinical benefit of remdesivir in SARS-CoV-2 infected macaques (bioRxiv) Remdesivir for MERS-CoV infection in macaques (PNAS) ChAdOX1 vaccination for SARS-CoV-2 in macaques ...
Source: This Week in Virology - MP3 Edition - Category: Virology Authors: Source Type: podcasts
Resumo Os sintomas respirat órios, principalmente o desenvolvimento de quadros de síndrome do desconforto respiratório agudo grave, dominam a discussão e as preocupações iniciais da população e dos profissionais de saúde. Entretanto, o sistema cardiovascular é bastante afetado por essas condições e, muitas vezes, é o responsável por complicações e mortalidade desses pacientes. Com o objetivo de mostrar as implicações cardiovasculares em pacientes infectados pela COVID-19 e a importância do iso...
Source: Arquivos Brasileiros de Cardiologia - Category: Cardiology Source Type: research
Resumo Os sintomas respirat órios, principalmente o desenvolvimento de quadros de síndrome do desconforto respiratório agudo grave, dominam a discussão e as preocupações iniciais da população e dos profissionais de saúde. Entretanto, o sistema cardiovascular é bastante afetado por essas condições e, muitas vezes, é o responsável por complicações e mortalidade desses pacientes. Com o objetivo de mostrar as implicações cardiovasculares em pacientes infectados pela COVID-19 e a importância do iso...
Source: Arquivos Brasileiros de Cardiologia - Category: Cardiology Source Type: research
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