Risk factors for limited improvement after total trapeziometacarpal joint arthroplasty

Trapeziometacarpal (TMC) osteoarthritis can be painful and cause disability for patients. Total joint replacement of the TMC joint provides a pseudo arthrosis with good restoration of the thumb motion and pain...
Source: Health and Quality of Life Outcomes - Category: International Medicine & Public Health Authors: Tags: Research Source Type: research

Related Links:

Abstract BACKGROUND: The Bernese periacetabular osteotomy (PAO) is one of the most-used surgical techniques to treat symptomatic acetabular dysplasia. Although good functional and radiographic short-term and long-term outcomes have been reported, several complications after PAO have been described. One complication that may compromise clinical results is nonunion of an osteotomy. However, the exact prevalence and risk factors associated with nonunion are poorly elucidated. QUESTIONS/PURPOSES: (1) What proportion of patients have complete bony healing versus nonunion during the first year after PAO? (2) What i...
Source: Clinical Orthopaedics and Related Research - Category: Orthopaedics Authors: Tags: Clin Orthop Relat Res Source Type: research
Weng and colleagues must be commended for their attempts to clarify the benefit/harm ratio of duloxetine in osteoarthritis and chronic low back pain1. Indeed, the high number of therapeutic options available shows the state of affairs is a lottery while these frequent conditions “associated with substantial work disability, morbidity, costs, and increased mortality rates” deserve robust evidence2. However, their conclusion “Duloxetine had modest to moderate effects… with mild adverse events” claiming “future randomized controlled trials should focus on comparing duloxetine…” deserves scrutiny.
Source: Osteoarthritis and Cartilage - Category: Rheumatology Authors: Tags: Letter to the Editor Source Type: research
To describe the value of radiographic- and MRI-defined tibiofemoral osteoarthritis (ROA and MRI-OA, respectively) and in combination for predicting tibial cartilage loss, knee pain and disability and total knee replacement (TKR) in a population-based cohort.
Source: Osteoarthritis and Cartilage - Category: Rheumatology Authors: Source Type: research
Osteoarthritis (OA) of the ankle joint is associated with life-long joint pain and disability if not appropriately managed. There is a dearth of research concerning ankle OA and the impact on those living with the condition.
Source: Physiotherapy - Category: Physiotherapy Authors: Source Type: research
Abstract INTRODUCTION: Osteoarthritis (OA) is characterised by synovial joint pain, functional disability and affects ∼13 % of people worldwide, of which ∼16-27 % report Knee-OA (KOA). Glucosamine (Glu) is the most widely used nutraceutical treatment for OA despite a lack of scientific consensus, therefore alternative nutraceutical treatments are required. The aim of this study was to investigate the effect of Lithothamnion species, seawater-derived magnesium and pine bark (Aq+) on pain, symptoms and improve physical function in symptomatic (sKOA), compared to Glu. METHODS: 358 participants were scree...
Source: Complementary Therapies in Medicine - Category: Complementary Medicine Authors: Tags: Complement Ther Med Source Type: research
Authors: Borisovskaya A, Chmelik E, Karnik A Abstract In this chapter, we describe the impact and etiology of chronic pain, the associated changes in the nervous system, and the mechanisms by which exercise may be able to affect and reverse these changes. Evidence for efficacy of exercise in different conditions associated with chronic pain is presented, with focus on chronic low back pain, fibromyalgia, osteoarthritis, rheumatoid arthritis, and migraines. While the efficacy of exercise and level of evidence supporting it vary in different diseases, exercise has direct and indirect benefits for most patients suffer...
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
In conclusion, our study demonstrated that Nrf2 deficiency promoted the increasing trend of autophagy during aging in skeletal muscle. Nrf2 deficiency and increasing age may cause excessive autophagy in skeletal muscle, which can be a potential mechanism for the development of sarcopenia. To What Degree is Chondrocyte Hypertrophy in Osteoarthritis Due to Cellular Senescence? https://www.fightaging.org/archives/2020/04/to-what-degree-is-chondrocyte-hypertrophy-in-osteoarthritis-due-to-cellular-senescence/ Senescent cells are large. They do not replicate, that function is disabled, but it is as if they go ...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Senescent cells are large. They do not replicate, that function is disabled, but it is as if they go to the effort of producing all the material needed for replication, and thus swell up in size. A lot of the distinctive behavior of senescent cells seems quite connected to the fact that they are large. Insofar as aging is concerned, the important aspects of senescent cells are (a) whether or not they are being cleared rapidly and efficiently enough to keep their numbers down, and (b) the inflammatory, damaging signals they secrete. As senescent cell numbers grow, they cause ever more dysfunction in the surrounding tissue a...
Source: Fight Aging! - Category: Research Authors: Tags: Medicine, Biotech, Research Source Type: blogs
ConclusionAs the high complication rate is compensated by a better functional outcome (enhanced range of motion and strength), we believe that prosthesis implantation can be a reasonable treatment option for carpometacarpal-I osteoarthritis in a particular patient group.Level of Evidence IIIl: Retrospective cohort study.
Source: European Journal of Medical Research - Category: Research Source Type: research
ConclusionIndividuals did not report an increase in knee pain, stiffness or disability in their ACL ‐deficient knee. Only disability was associated with worsening severity of radiographic OA in ACL‐deficient knees.
Source: International Journal of Rheumatic Diseases - Category: Rheumatology Authors: Tags: ORIGINAL ARTICLE Source Type: research
More News: Disability | International Medicine & Public Health | Orthopaedics | Osteoarthritis | Pain