Clinical Study of Meplazumab to Treat With Malaria

Condition:   Malaria (Plasmodium Falciparum) Interventions:   Drug: Meplazumab for Injection;   Drug: Sterile normal saline (0.9%) Sponsor:   Jiangsu Pacific Meinuoke Bio Pharmaceutical Co Ltd Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials

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Sanofi has temporarily stopped recruiting new COVID-19 patients for two clinical trials on hydroxychloroquine and will no longer supply the anti-malaria drug to treat COVID-19 until concerns about safety are cleared up, it said on Friday.Reuters Health Information
Source: Medscape Critical Care Headlines - Category: Intensive Care Tags: Infectious Diseases News Source Type: news
US hospitals said they have pulled way back on the use of hydroxychloroquine, the malaria drug touted by President Donald Trump as a COVID-19 treatment, after several studies suggested it is not effective and may pose significant risks.Reuters Health Information
Source: Medscape Critical Care Headlines - Category: Intensive Care Tags: Infectious Diseases News Source Type: news
[Ghanaian Times] Wa -The AGA Mal-AngloGold Malaria Control Programme has provided a US$300,000 support package to the Upper West Region to help in the management of the Coronavirus (CODVID-19) pandemic.
Source: AllAfrica News: Malaria - Category: Infectious Diseases Source Type: news
To the Editor I was alarmed to read the recent JAMA Internal Medicine article by Bao et al suggesting that pyrethroid insecticide exposure is associated with a 3-fold increase in the risk of adult mortality from cardiovascular disease. The significance of this finding cannot be overstated, should it be replicated and shown to be true. The world relies heavily on pyrethroids for the control of vector-borne diseases, including malaria. Huge advances have been made over the past 20 years in malaria control —we have cut transmission by about half, primarily using pyrethroid-treated mosquito nets, and prevented millions o...
Source: JAMA Internal Medicine - Category: Internal Medicine Source Type: research
This study provides an approach for estimating health district-level malaria readiness indicators from survey data designed to provide regionally representative estimates. A binomial-hierarchical Bayesian spatial prediction method was applied to Burkina Faso Service Availability and Readiness Assessment (SARA) survey data to provide estimates of essential equipment availability and readiness for malaria care. Predicted values of each indicator were adjusted by the type of health facility, location, and population density. Then, a health district composite readiness profile was built via hierarchical ascendant classificatio...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
lenburg Despite having reported one of the highest maternal mortality ratios and neonatal mortality rates in the world, surprisingly little is known about the general health status of pregnant women in rural parts of Sierra Leone. Malaria, anaemia and malnutrition are known contributors to adverse pregnancy outcomes. Although their prevalence is known to be high, the burden of these conditions in the rural pregnant population remains unknown. Our study aimed to gain more insight into the health status of pregnant women. An observational retrospective descriptive study was conducted at the Lion Heart Medical Centre usin...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
This study shows that the magnitude of the host transcriptional response can differ markedly from related parasites with different virulence, and it enables a better understanding of the molecular interactions taking place between hosts and parasites. PMID: 32469658 [PubMed - as supplied by publisher]
Source: The American Naturalist - Category: Biology Authors: Tags: Am Nat Source Type: research
(Georgia Institute of Technology) The malaria drug hydroxychloroquine, which has been promoted as a potential treatment for Covid-19, is known to have potentially serious effects on heart rhythms. Now, a team of researchers has used an optical mapping system to observe exactly how the drug creates serious disturbances in the electrical signals that govern heartbeat.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
[Los aptámeros como novedosa herramienta diagnóstica y terapéutica y su potencial uso en parasitología]. Biomedica. 2020 May 01;40(Supl. 1):148-165 Authors: Ospina JD Abstract Los aptámeros son secuencias de ADN o ARN de cadena sencilla que adoptan la forma de estructuras tridimensionales únicas, lo cual les permite reconocer un blanco específico con gran afinidad. Sus usos potenciales abarcan, entre otros, el diagnóstico de enfermedades, el desarrollo de nuevos agentes terapéuticos, la detección de riesgos alimentarios, la producci&...
Source: Biomedica : Revista del Instituto Nacional de Salud - Category: International Medicine & Public Health Tags: Biomedica Source Type: research
Sanofi has temporarily stopped recruiting new COVID-19 patients for two clinical trials on hydroxychloroquine and will no longer supply the anti-malaria drug to treat COVID-19 until concerns about safety are cleared up, it said on Friday.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
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