Wastewater test could provide early warning of COVID-19
(Cranfield University) Researchers at Cranfield University are working on a new test to detect SARS-CoV-2 in the wastewater of communities infected with the virus. The wastewater-based epidemiology (WBE) approach could provide an e?ective and rapid way to predict the potential spread of novel coronavirus pneumonia (COVID-19) by picking up on biomarkers in faeces and urine from disease carriers that enter the sewer system.
CONCLUSIONS: Further studies are required in order to establish the complicated association between SARS-CoV-2 infection and its effects on the cardiovascular system. Our knowledge regarding diagnostic approaches, therapeutic management and preventive measures is constantly enriched throughout an abundance of ongoing research in the respective fields. PMID: 32472990 [PubMed - as supplied by publisher]
We report the case of a 50-year-old man affected by SARS-CoV-2 pneumonia, who developed acute pulmonary embolism.
Conclusions: The outbreak of the epidemic could promote coronavirus research, meanwhile, coronavirus research contributes to overcoming the epidemic. Attention should be drawn to the latest popular research, including “Spike protein,” “Receptor binding domain,” and “Vaccine.” Therefore, more and more efforts will be put into mechanism research and vaccine research and development, which can be helpful to deal with the epidemic.
In December 2019, multiple cases of atypical pneumonia of unknown origin were detected in China. At the same time, a new coronavirus subtype was discovered as the etiology behind these described cases in Wuhan, Hubei (China). This novel microorganism detected, called as severe acute respiratory syndrome coronavirus 2 (SARS-COV-2), has an enormous virulence and a high human-to-human transmission capacity [1 –2]. Thanks to its virulence, the SARS-COV-2 has been able to spread throughout the world, creating the unprecedented pandemic in which we are involved.
onikaki The coronavirus disease, COVID-19, caused by the novel coronavirus SARS-CoV-2, which first emerged in Wuhan, China and was made known to the World in December 2019 turned into a pandemic causing more than 126,124 deaths worldwide up to April 16th, 2020. It has 79.5% sequence identity with SARS-CoV-1 and the same strategy for host cell invasion through the ACE-2 surface protein. Since the development of novel drugs is a long-lasting process, researchers look for effective substances among drugs already approved or developed for other purposes. The 3D structure of the SARS-CoV-2 main protease was compared with th...
Coronaviruses are pathogens that target the human respiratory system. Previous outbreaks of coronaviruses include severe acute respiratory syndrome (SARS)  and Middle East respiratory syndrome (MERS) . In December, 2019, an outbreak of pneumonia of unknown cause was reported in Wuhan, China . Chinese scientists rapidly identified the causative agent as a novel coronavirus (SARS-CoV-2) by sequencing the complete genome from lower respiratory tract samples of patients in Wuhan . The WHO named this disease “coronavirus disease 2019” (COVID-19).
The novel coronavirus 2 (SARS-CoV-2) was first described in Wuhan, China, in December 2019, and causes the infectious disease; COVID-19, which has been declared a pandemic by the World Health Organization. COVID-19 pneumonia may lead to acute respiratory distress syndrome and severe respiratory failure . Other complications include myocarditis, renal failure and neurological involvement .
AbstractThe novel coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is sorely testing health care systems and economies around the world and is rightly considered as the major health emergency in a century. Despite the course of the disease appearing to be mild in many cases, a significant proportion of symptomatic patients develop pneumonia requiring hospitalisation or progress to manifest respiratory complications leading to intensive care treatment. Potential interventions for SARS-CoV2-associated pneumonia are being tested, some of which holding promise,...
A number of pneumonia cases of unknown causes have emerged in Wuhan, Hubei, China since December 2019.1 After sequencing analysis of samples from the lower respiratory tract, a coronavirus,2 which was last named as severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2).3 On February 11, 2020, the World Health Organization (WHO) announced a new name for the disease caused by 2019-nCoV: coronavirus disease 2019 (COVID-19).4 With the arrival of the Spring Festival, an epidemic SARS-CoV-2 infection has spread rapidly.
Conclusions and Relevance: Because there are 74.0 million children 0 to 17 years old in the United States, the projected numbers of severe cases could overextend available pediatric hospital care resources under several moderate CPIP scenarios for 2020 despite lower severity of COVID-19 in children than in adults.