Structural Model for Estimating the Influence of Healthy Lifestyle on Episodic Memory in Adults with Subjective Memory Complaints.
Structural Model for Estimating the Influence of Healthy Lifestyle on Episodic Memory in Adults with Subjective Memory Complaints. Biomed Res Int. 2020;2020:8349819 Authors: Li S, Tang Y Abstract The aim of this study is to examine the relationships between a healthy lifestyle and episodic memory among adults with subjective memory complaints (SMCs). We proposed a structure equation model to study the association between a healthy lifestyle and episodic memory with an investigation covering 309 participants over 50 years old with SMCs. The model showed a good fit after being adjusted (p = 0.054, goodness of fit index = 0.981, adjusted goodness of fit index = 0.956, comparative fit index = 0.981, and root mean square error of approximation = 0.049): a healthy lifestyle has a direct positive effect on episodic memory among adults with SMCs (β = 0.60). The research model provides possible guidelines for medical staff to prevent the cognitive function decline in the risk population of Alzheimer's disease. PMID: 32219143 [PubMed - as supplied by publisher]
FDA approved Tauvid for IV injection, the first drug used to help image a distinctive characteristic of Alzheimer ’s disease in the brain called tau pathology. Tauvid is a radioactive diagnostic agent for adult patients with cognitive impairment who are being evaluated for Alzheimer’s disease.
Conclusions: AD and CVD are frequently associated. Further studies are needed in order to understand the effect of CVD and its risk factors on AD in order to better comprehend the effects of subclinical and clinical CVD on the brain. Finally, we need to clarify the impact of the underlying hypothesized mechanisms of this association and to investigate gender issues. PMID: 32454996 [PubMed]
Older people who have large body weight fluctuations may have an increased risk for developing dementia and Alzheimer’s, according to a study published inFrontiers in Endocrinology. Endocrinology Advisor
CONCLUSION: Limbic-predominant age-related TDP-43 encephalopathy is uniquely associated with distinct longitudinal profiles of financial and health literacy in old age. PMID: 32452861 [PubMed - as supplied by publisher]
Publication date: June 2020Source: The Lancet Neurology, Volume 19, Issue 6Author(s): Yakeel T Quiroz, Henrik Zetterberg, Eric M Reiman, Yinghua Chen, Yi Su, Joshua T Fox-Fuller, Gloria Garcia, Andres Villegas, Diego Sepulveda-Falla, Marina Villada, Joseph F Arboleda-Velasquez, Edmarie Guzmán-Vélez, Clara Vila-Castelar, Brian A Gordon, Stephanie A Schultz, Hillary D Protas, Valentina Ghisays, Margarita Giraldo, Victoria Tirado, Ana Baena
Publication date: June 2020Source: The Lancet Neurology, Volume 19, Issue 6Author(s): Colin L Masters
Contributors : Kirk B Burkhart ; Steven R Sando ; Anna Corrionero ; H R HorvitzSeries Type : Expression profiling by high throughput sequencingOrganism : Caenorhabditis elegansMaternally inherited RNA and protein control much of embryonic development. The impact of such maternal information beyond embryonic development is largely unclear. Here we report that maternal contribution of histone H3.3 assembly complexes can prevent the expression of late-onset anatomical, physiologic, and behavioral abnormalities of C. elegans. We show that mutants lacking hira-1, an evolutionarily conserved H3.3-deposition factor, have severe p...
Publication date: Available online 26 May 2020Source: Journal of Chemical NeuroanatomyAuthor(s): Mahdi Ramezani, Alireza Komaki, Nasrin Hashemi-Firouzi, Keywan Mortezaee, Nafiseh Faraji, Zoleikha Golipoor
Photo credit Aris Fackenakis The truth, as they see it, is still the truth in their eyes. Delusions, hallucinations, agitation, aggression, and depression are all part of the gradual progression of psychosis of patients with Alzheimer ’s disease (AD). An average of 41% of these patients will experience these psychotic symptoms. One of the most common delusions these patients have are theft-related. An experienced caregiver offers her advice on how to deal with accusations of theft, which are common in dementia patients. Continue reading on Agingcare for more about how Alzheimer's - yes even younger-onset Alzheimer's ...
Mucus is integral to gut health and its properties may be affected in neurological disease. Mucus comprises a hydrated network of polymers including glycosylated mucin proteins. We propose that factors that influence the nervous system may also affect the volume, viscosity, porosity of mucus composition and subsequently, gastrointestinal (GI) microbial populations. The gut has its own intrinsic neuronal network, the enteric nervous system, which extends the length of the GI tract and innervates the mucosal epithelium. The ENS regulates gut function including mucus secretion and renewal. Both dysbiosis and gut dysfunction a...