The combination between NCSTN gene copy number variation and growth traits in Chinese cattle.

The combination between NCSTN gene copy number variation and growth traits in Chinese cattle.
Anim Biotechnol. 2020 Mar 25;:1-5
Authors: Yao YF, Lyu S, Wang X, Zhang Z, Qu K, Xu J, Cai C, Li Z, Xie J, Ru B, Xu Z, Wang E, Lei C, Chen H, Huang B, Huang Y
Abstract
Copy number variation (CNV) has been used as an important source of phenotypic and genetic diversity in recent years. Nicastrin (NCSTN) gene is usually attached to human diseases such as Alzheimer's disease, and Acne inversa. However, there are no essays about the NCSTN gene combining with cattle breeds. In our study, we discovered different distributions of NCSTN gene copy number and associated it with phenotypic traits in four Chinese yellow cattle breeds (XN, PN, QC and YL). The result turned out that the CNV of the NCSTN gene was associated with several growth traits, such as cannon circumference, chest girth and rump length (p < 0.05). In general, we revealed the eminence over CNV of NCSTN gene and economic traits, suggesting that the CNV of the NCSTN gene can be considered to be a promising molecular breeding marker of Chinese beef cattle.
PMID: 32208881 [PubMed - as supplied by publisher]

Source: Animal Biotechnology - March 24, 2020 Category: Biotechnology Authors: Yao YF, Lyu S, Wang X, Zhang Z, Qu K, Xu J, Cai C, Li Z, Xie J, Ru B, Xu Z, Wang E, Lei C, Chen H, Huang B, Huang Y Tags: Anim Biotechnol Source Type: research