Mutant Huntingtin affects toll-like receptor 4 intracellular trafficking and cytokine production in mast cells

Huntington ’s disease (HD) is caused by the expression of a mutated variant of Huntingtin (mHtt), which results in the complex pathology characterized by a defective function of the nervous system and altered i...

Source: Journal of Neuroinflammation - March 27, 2020 Category: Neurology Authors: Marian Jesabel P érez-Rodríguez, Alfredo Ibarra-Sánchez, Abraham Román-Figueroa, Francisca Pérez-Severiano and Claudia González-Espinosa Tags: Research Source Type: research