Peanut applied to the skin of nonhuman primates induces antigen ‐specific IgG but not IgE

ConclusionsSkin exposure to peanut did not lead to sensitization in this study, and monkeys did not experience anaphylaxis upon peanut challenge. However, monkeys produced increased peanut ‐specific IgG throughout peanut exposure, indicating that repeated skin exposure to peanut is immunogenic.

Source: Immunity, Inflammation and Disease - March 28, 2020 Category: Allergy & Immunology Authors: Michael D. Kulis, Johanna M. Smeekens, Kylie Kavanagh, Matthew J. Jorgensen Tags: ORIGINAL RESEARCH Source Type: research