Gender differences in blood transfusion strategy for patients with hip fractures - a retrospective analysis.
Conclusion: Over the course of five years, a restrictive transfusion strategy was implemented within clinical practice in patients undergoing surgery for hip fractures. In parallel, a significant reduction in the hospital LOS and an increased ICU LOS was noted. Whether there is an association between increased ICU LOS and decreasing hospital LOS and whether there is a gender effect on transfusion requirements in patients with surgery for hip fractures should be subject to further research. PMID: 32210711 [PubMed - in process]
Authors: Stubbs JR, Jenkins DH Abstract Mass casualty incidents (MCI) are high profile contributors to the number of annual trauma-related deaths in the United States. A critical aspect of MCI care is the ability to provide blood components in sufficient types and quantities to prevent deaths due to hemorrhage. For transfusions to play an optimal role in the prevention of trauma-related hemorrhagic death, including MCI, there appears to be a very tight time window after injury to initiate transfusion therapy. In order to meet this tight window, blood components of appropriate numbers and quantities must be immediat...
Condition: Transfusion Intervention: Sponsor: Johann Wolfgang Goethe University Hospital Not yet recruiting
DISCUSSION: In summary, treatment of RBCs with PIPA prior to RCE elicited favourable or neutral changes in key metabolic and vascular biomarkers. Further study of its efficacy and safety is recommended and could ultimately serve to improve outcomes in chronically transfused SCD patients. PMID: 32203007 [PubMed - as supplied by publisher]
We describe our own institutional experience using a targeted CDS to promote restrictive blood transfusion practice and to improve RBC use. A 42% reduction in RBC transfusions was demonstrated at our institution from a baseline in 2008 through 2015, and the rate remained stable through 2018. Although the data cannot be used to infer causality, this decreased RBC use was accompanied by improved clinical outcomes. PMID: 31808902 [PubMed - in process]
Condition: Myelodysplatic Syndromes Intervention: Other: Physiological tests to measure fatigue level Sponsors: Institut de Cancérologie de la Loire; Laboratoire Interuniversitaire de Biologie de la Motricité - Jean Monnet University Saint-Etienne Not yet recruiting