Molecules, Vol. 25, Pages 1509: New Chlorinated 2,5-Diketopiperazines from Marine-Derived Bacteria Isolated from Sediments of the Eastern Mediterranean Sea
Molecules, Vol. 25, Pages 1509: New Chlorinated 2,5-Diketopiperazines from Marine-Derived Bacteria Isolated from Sediments of the Eastern Mediterranean Sea
Molecules doi: 10.3390/molecules25071509
Authors:
Maria Harizani
Eleni Katsini
Panagiota Georgantea
Vassilios Roussis
Efstathia Ioannou
From the organic extracts of five bacterial strains isolated from marine sediments collected in the East Mediterranean Sea, three new (15, 16, 31) and twenty-nine previously reported (1–14, 17–30, 32) metabolites bearing the 2,5-diketopiperazine skeleton were isolated. The structures of the chlorinated compounds 15, 16, and 31 were elucidated by extensive analysis of their spectroscopic data (NMR, MS, UV, IR). Compounds 15 and 16 were evaluated for their antifungal activity against Candida albicans and Aspergillus niger but were proven inactive. The relevant literature is supplemented with complete NMR assignments and revisions for the 29 previously reported compounds.
Source: Molecules - Category: Chemistry Authors: Maria Harizani Eleni Katsini Panagiota Georgantea Vassilios Roussis Efstathia Ioannou Tags: Article Source Type: research