Response to MM Rojas-Rojas et al

We thank MM Rojas-Rojas et al. for their interest in our article investigating the role of multi-parametric MRI in squamous cell carcinoma of the anal canal (SCCAC) [1]. They raise concerns regarding the variability of diffusion weighted image acquisition between centres and reference an editorial [2] citing two multi-centre studies that reported poor agreement of apparent diffusion coefficient values between sites [3,4]. Unfortunately, both of these studies failed to fully standardise MRI sequences between centres, which may explain the observed inconsistencies.

Source: Radiotherapy and Oncology - March 25, 2020 Category: Radiology Authors: Michael Jones, Jarad Martin Tags: Letter to the Editor Source Type: research