Utility of urinary ctDNA to monitoring minimal residual disease in early breast cancer patients.

CONCLUSION: Urinary DNA offers non-invasive probing and real-time monitoring of breast cancer relapse. Our results demonstrated clear clinical relevance in breast cancer and significant risk profiling of early breast cancer patients. This potentially aids to complement current cancer relapse monitoring and may help in early intervention. PMID: 32176625 [PubMed - as supplied by publisher]
Source: Cancer Biomarkers - Category: Cancer & Oncology Tags: Cancer Biomark Source Type: research

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Suppose you’re the sole witness of a trolley that has gone out of control, hurtling towards 5 people tied to its track, with no way to stop it in time. Good news: there’s a lever you can pull to alter its direction. Bad news: the other track isn’t safe either as it has one person tied to it. What will you do in this situation? Let the trolley continue on its initial course and kill those 5 people on the way or pull the lever to save them at the expense of that other person’s life? Source: https://www.lionsroar.com/ This ethical thought experiment, known as the Trolley Problem, was put forth by...
Source: The Medical Futurist - Category: Information Technology Authors: Tags: Artificial Intelligence Bioethics Future of Medicine Healthcare Policy covid19 Source Type: blogs
In this systematic review, researchers highlighted the strengths and weaknesses of existing decision aids for women with an average risk of breast cancer who are eligible for mammographic screening.
Source: CancerNetwork - Category: Cancer & Oncology Authors: Source Type: news
Authors: Ceccarelli M, Venanzi Rullo E, Marino MA, d'Aleo F, Pellicanò GF, D'Andrea F, Marino A, Cacopardo B, Celesia BM, La Rocca G, Di Rosa M, Condorelli F, Berretta M, Nunnari G Abstract The increasing incidence of chronic pathologies and especially non-AIDS defining cancers, such as lung cancer, hepatocellular carcinoma, breast cancer, colorectal cancer, prostate cancer, and Hodgkin's lymphoma after the introduction of combined antiretroviral therapy requires the infectious diseases specialist to know how and when to suspect and diagnose cancer in people living with HIV. The aim of this review is to prov...
Source: European Review for Medical and Pharmacological Sciences - Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
CONCLUSIONS: We developed a novel way of visualizing uncertainties in recurrence rates in a patient decision aid. The effect of this way of communicating risk uncertainty is currently being tested in the BRASA study (NCT03375801). PMID: 32298961 [PubMed - as supplied by publisher]
Source: Breast - Category: Cancer & Oncology Authors: Tags: Breast Source Type: research
AbstractNovel adjunctive screening aids are needed to reduce the morbidity and mortality related to cancer, and every effort should be made for early diagnosis. This systematic review aimed to evaluate salivary metabolites and their diagnostic value in patients with cancer.The systematic review was performed in two phases and included studies that focused on the diagnostic value of salivary metabolites in humans with solid malignant neoplasms. Five electronic databases were searched, and the risk of bias in individual studies was evaluated using the revised Quality Assessment of Diagnostic Accuracy Studies criteria (QUADAS...
Source: International Journal of Clinical Oncology - Category: Cancer & Oncology Source Type: research
More individuals within the U.S. suffer from traumatic brain injuries (TBI) than breast cancer or HIV/aids and is one of the leading causes of disability. Due to the prevalence and severity of TBIs, it is essential for couple, marriage, and family therapis...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news
The future of healthcare is shaping up in front of our very eyes with advances in digital technologies, such as artificial intelligence, VR/AR, 3D-printing, robotics or nanotechnology. We have to familiarize with the latest developments in order to be able to control technology and not the other way around. The future of healthcare lies in working hand-in-hand with technology and healthcare workers have to embrace emerging technologies in order to stay relevant in the coming years. Be bold, curious and informed! Are you afraid that robots will take over the jobs of nurses, doctors and other healthcare professionals? Are y...
Source: The Medical Futurist - Category: Information Technology Authors: Tags: Future of Medicine 3d printing AI artificial intelligence augmented reality genetics Health Healthcare nanotechnology Personalized medicine pharma pharmacology robotics virtual reality wearables GC1 Source Type: blogs
Several indicators on pretreatment FDG-PET/CT scans can help predict overall...Read more on AuntMinnie.comRelated Reading: Biomarkers on PET, MRI show breast cancer risk FDG-PET/CT within a year of heart valve surgery looks safe FDG-PET/CT helps predict tuberculosis relapse 2 new PET tracers may best FDG in cancer imaging FDG-PET/CT aids in melanoma treatment assessment
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
In a finding they described as "unexpected," researchers used PET and MRI to...Read more on AuntMinnie.comRelated Reading: Can FDG-PET/MRI replace biopsy in breast cancer cases? TOF PET/MRI makes dose reduction viable for breast cancer PET tracers help guide breast cancer therapies Can dedicated breast PET identify suspicious lesions? FDG-PET/CT aids assessment of lower-stage breast cancer
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
Paul Cerrato and I have created a new book,Reinventing Clinical Decision Support, our first to be published about Platform thinking.  Although it is being published during my tenure at Mayo Clinic, it is not endorsed by Mayo Clinic and represents the personal opinions of Paul and me.  Below is the preface.In our last book, on mobile health(1),  we wrote about the power of words such as cynicism, optimism, and transformation. Another word with powerful connotations is misdiagnosis. To a patient whose condition remains undetected, it is a source of frustration and anger. To a physician or nurse who has be...
Source: Life as a Healthcare CIO - Category: Information Technology Source Type: blogs
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