New insights into the obesity paradox in renal cell carcinoma

Nature Reviews Nephrology, Published online: 02 March 2020; doi:10.1038/s41581-020-0264-yParadoxically, elevated BMI is a recognized positive prognostic factor in renal cell carcinoma (RCC). A recent investigation of the transcriptomic signatures of RCC tumours and peritumoural tissues suggests potential biological mechanisms underlying this effect. However, the clinical utility of BMI in the context of RCC remains uncertain.

http://feeds.nature.com/~r/nrneph/rss/current/~3/4-o8MwTM4pA/s41581-020-0264-y

Source: Nature Reviews Nephrology - March 1, 2020 Category: Urology & Nephrology Authors: Chun Loo Gan Daniel Y. C. Heng Source Type: research