Positive effects of the young systemic environment and high GDF ‐11 levels on chondrocyte proliferation and cartilage matrix synthesis in old mice

ConclusionThe young systemic environment promotes chondrocyte proliferation and cartilage matrix synthesis in old mice. GDF11, a young factor, contributes to these effects by the up ‐regulation pSmad2/3.

Source: Arthritis and Rheumatology - February 27, 2020 Category: Rheumatology Authors: Lu Li, Xiaochun Wei, Dongming Wang, Zhi Lv, Xiang Geng, Pengcui Li, Jiangong Lu, Kaihang Wang, Xiaohu Wang, Jian Sun, Xiaoming Cao, Lei Wei Tags: FULL LENGTH Source Type: research