Oral typhoid vaccine Ty21a elicits antigen-specific resident memory CD4+ T cells in the human terminal ileum lamina propria and epithelial compartments

Salmonella enterica serovar Typhi (S. Typhi) is a highly invasive bacterium that infects the human intestinal mucosa and causes ~  11.9–20.6 million infections and ~ 130,000–223,000 deaths annually worldwide. Oral...

Source: Journal of Translational Medicine - February 25, 2020 Category: Research Authors: Jayaum S. Booth, Eric Goldberg, Robin S. Barnes, Bruce D. Greenwald and Marcelo B. Sztein Tags: Research Source Type: research