Uterine Dnmt3a is not required for mouse embryo implantation.

CONCLUSION: Overall, these results demonstrated that although some decidual markers are expressed abnormally, conditional knockout of Dnmt3a in the uterus did not significantly affect the endometrial function during embryo implantation; the embryo could implant into the endometrium normally.
PMID: 32096741 [PubMed - as supplied by publisher]

Source: Current Molecular Medicine - February 23, 2020 Category: Molecular Biology Authors: Li N, Lu S, Ding Y, Chen X, He J, Liu X, Chen M, Zhang J, Su Y, Zhang X, Wang Y, Gao R Tags: Curr Mol Med Source Type: research