Efficacy and safety of dimeticones in the treatment of epidermal parasitic skin diseases with special emphasis on tungiasis: an evidence-based critical review
Publication date: Available online 24 February 2020Source: The Brazilian Journal of Infectious DiseasesAuthor(s): Hollman Miller, Julián Trujillo-Trujillo, Francis Mutebi, Hermann Feldmeier
Publication date: Available online 3 April 2020Source: International Journal for Parasitology: Parasites and WildlifeAuthor(s): Anna M. Pyziel, Aleksander W. Demiaszkiewicz, Barbara Osińska, Izabella Dolka, Krzysztof Anusz, Zdzisław Laskowski
AbstractMalaria, an important parasitic disease worldwide, still has diagnostic challenges in the laboratory. Many studies have been conducted on the detection ability of haematology analysers for malaria. We evaluated the Sysmex XN-series analyser as a tool for detection of malaria by analysing the leukocyte cell population data (LCPD), scattergrams and associated Flow Cytometry Standard (FCS) data from both the WNR (white cell nucleated) and WDF (white cell differential) channels. 1281 clinically suspected cases of malaria were screened for malaria by peripheral blood smear examination and were run in the Sysmex XN-1000 ...
We present a case of a previously healthy 60-year-old woman who developed an illness strongly suggestive of ATBF after a missionary trip to Zimbabwe and discuss the disease's diagnostic challenges. Our paper also reviews the epidemiology of this disease and the currently available diagnostic laboratory tests and recommended treatment options. PMID: 32226336 [PubMed - in process]
(Virginia Tech) In a new study published in GLIA , Virginia Tech neuroscientists at the Fralin Biomedical Research Institute at VTC describe how the common Toxoplasma gondii parasite prompts the loss of inhibitory signaling in the brain by altering the behavior of nearby cells called microglia.
In this study, we analysed the effect of glutamine analogues on the parasite life cycle. Here, we show that glutamine analogues impair cell proliferation, the developmental cycle during the infection of mammalian host cells and metacyclogenesis. Taken together, these results show that glutamine is an important metabolite for T. cruzi survival and suggest that glutamine analogues can be used as scaffolds for the development of new trypanocidal drugs. These data also reinforce the supposition that glutamine metabolism is an unexplored possible therapeutic target.
by Catherine S. Nation, Akram A. Da ’dara, Jeffrey K. Marchant, Patrick J. Skelly Schistosomes are parasitic blood flukes that infect>200 million people around the world. Free-swimming larval stages penetrate the skin, invade a blood vessel, and migrate through the heart and lungs to the vasculature of the liver, where maturation and mating occurs. From here, the parasite couples migrate to their preferred egg laying sites. Here, we compare and contrast what is known about the migration patterns within the definitive host of the three major species of human schistosome:Schistosoma mansoni,S.japonicum, andS.haemat...
Abstract An original voltammetric screening method, employing glassy carbon electrode (GCE) with the differential-pulse voltammetry technique (DPV), has been developed to determine residues of the anti-parasitic agent Ronidazole (RNZ) in bovine meat. By using cyclic voltammetry (CV), it has been demonstrated that an irreversible cathodic process occurs at approximately -0.740 V (vs. Ag|AgCl, KCl 3 mol L-1) in a 0.100 mol L-1 phosphate buffer at pH 6.5 as supporting electrolyte. Furthermore, the behavior of RNZ in CV indicates the occurrence of a diffusion mass transfer process to the working e...
Publication date: Available online 31 March 2020Source: Zoologischer AnzeigerAuthor(s): Aïssatou Bâ, Bernard Marchand, Papa Ibnou Ndiaye, Cheikh Tidiane Bâ, Abdoulaye J.S. Bakhoum, Rodney Alan Bray, Yann Quilichini
(University of Helsinki) A precise statistical analysis reveals that on the Å land Islands a powdery mildew fungus that is a common parasite of the ribwort plantain primarily spreads via roadsides because traffic raises the spores found on roadsides efficiently into the air.
Publication date: Available online 31 March 2020Source: Fish &Shellfish ImmunologyAuthor(s): Xia Liu, Yongyao Yu, Dacheng Qin, Zixi Song, Zhenyu Huang, Kaifeng Meng, Jiafeng Cao, Fangzheng Xu, Gaofeng Cheng, Wei Ji, Zhen Xu