Assessing Cardiac Risk in Pregnant Women with Heart Disease: How risk scores are created and their role in clinical practice

Publication date: Available online 24 February 2020Source: Canadian Journal of CardiologyAuthor(s): Rohan D. D’Souza, Candice K. Silversides, George A. Tomlinson, Samuel C. Siu
Source: Canadian Journal of Cardiology - Category: Cardiology Source Type: research

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Fetal congenital heart disease (FHD) is a common and serious congenital malformation in children. In Asia, FHD birth defect rates have reached as high as 9.3%. For the early detection of birth defects and mortality, echocardiography remains the most effective method for screening fetal heart malformations. However, standard echocardiograms of the fetal heart, especially four-chamber view images, are difficult to obtain. In addition, the pathophysiological changes in fetal hearts during different pregnancy periods lead to ever-changing two-dimensional fetal heart structures and hemodynamics, and it requires extensive profes...
Source: IEE Transactions on Medical Imaging - Category: Biomedical Engineering Source Type: research
Dr. Laura Mulvey, 33, practices emergency medicine at Maimonides Medical Center in Brooklyn, New York. After spending six days receiving treatment in her own hospital, she is now recovering at home from what is presumed to be COVID-19, though her test was inconclusive. What follows is a lightly-edited transcript of her story as told to TIME. Early on, sometime in February, [COVID-19] was something that people were thinking about. And worried about. Certainly, the worries were not what they are now. But hospital-wise, we had a bit of an earlier jump on it, because we recognized that this was a potential threat. We’re ...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized COVID-19 UnitedWeRise20Disaster Source Type: news
Discussion Tachycardia is a rapid heart rate that is above normal for age and level of exertion. Tachycardia is common, particularly sinus tachycardia due to normally encountered circumstances such as pain, fever or exercise. It is usually a normal physiologic process but sustained tachycardia often indicates a potentially abnormal underlying cause. Sinus tachycardia has a rapid heart rate with normal P waves and P-R intervals and variations from moment to moment and respiration. Generally it is not over 200 beats/minute. Vagal stimulation can slow the heart rate; this is a gradual slowing, not an abrupt slowing seen in ...
Source: PediatricEducation.org - Category: Pediatrics Authors: Tags: Uncategorized Source Type: news
CONCLUSIONS: The fetal cerebral vascular response to MH varies based on underlying CHD diagnosis, suggesting that cardiovascular physiology may influence autoregulatory capacities of the fetal brain. Further studies are needed to determine clinical implications of these findings on long-term neurodevelopment in these at-risk children. This article is protected by copyright. All rights reserved. PMID: 32202689 [PubMed - as supplied by publisher]
Source: The Ultrasound Review of Obstetrics and Gynecology - Category: Radiology Authors: Tags: Ultrasound Obstet Gynecol Source Type: research
RARITAN, N.J., March 20, 2020 – The Janssen Pharmaceutical Companies of Johnson &Johnson announced today that it will unveil late-breaking data from its leading cardiovascular and metabolism portfolio during the virtual American College of Cardiology’s 69th Annual Scientific Session together with the World Congress of Cardiology (ACC.20/WCC) on March 28-30, 2020. Notably, four late-breaking abstracts for XARELTO® (rivaroxaban) will be presented, including data from the Phase 3 VOYAGER PAD study in patients with symptomatic peripheral artery disease (PAD) after lower-extremity revascularization.Click to ...
Source: Johnson and Johnson - Category: Pharmaceuticals Source Type: news
To analyze pregnancy outcomes of patients with heart disease in a single center and to explore the risk factors of adverse outcomes. 1033 pregnant women with heart disease were retrospectively included from 2010 to 2017. We collected data of maternal, obstetric, and fetal outcomes. Among 1086 pregnancies, 295 (27.1%) with congenital heart disease (CHD), 244 (22.5%) with rheumatic heart disease (RHD), 387 (35.6%) with arrhythmia, and 55 (5.1%) with cardiomyopathy. There were 8 (0.7%) maternal deaths.
Source: The American Journal of Cardiology - Category: Cardiology Authors: Source Type: research
We report a new class of natural-product-inspired covalent inhibitors of telomerase that target the catalytic active site. Age-Related Epigenetic Changes that Suppress Mitochondrial Function https://www.fightaging.org/archives/2020/03/age-related-epigenetic-changes-that-suppress-mitochondrial-function/ Today's open access research reports on two specific epigenetic changes observed in old individuals that act to reduce mitochondrial function. This joins an existing list of genes for which expression changes are known to impact mitochondrial function with age. A herd of hundreds of mitochondria are found ...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
(CNN) — The coronavirus has infected more than 100,000 people worldwide. With all of the news of event cancellations, empty flights and health precautions (wash your hands!), it’s natural that people may get a little anxious every time they feel a tickle in their throat or the beginnings of a bad cough. While the coronavirus is certainly something to take seriously, the chances of any individual person getting it are still low. But if you’re wondering whether that stuffy nose could end up being a worst case scenario, CNN talked to Dr. Greg Poland, a professor of medicine and Infectious diseases at the May...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Health News CNN Coronavirus Source Type: news
CONCLUSIONS: The indications for obstetrics ICU admission correlated with the proximate causes of maternal arrest observed worldwide. While obstetric hemorrhage is often unpredictable, deterioration of heart disease is foreseeable. Attention should be directed specifically toward improving the diagnosis and treatment of maternal heart disease during pregnancy in Israel. PMID: 32147977 [PubMed - in process]
Source: The Israel Medical Association Journal - Category: General Medicine Tags: Isr Med Assoc J Source Type: research
Publication date: Available online 6 March 2020Source: European Journal of Obstetrics &Gynecology and Reproductive BiologyAuthor(s): Annelieke H.J. Petrus, Britt L. Jongert, Philippine Kiès, Marieke Sueters, Monique R.M. Jongbloed, Hubert W. Vliegen, Martin J. Schalij, Jan van Lith, Thomas van den Akker
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - Category: OBGYN Source Type: research
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