Effect of Rewarming on Leukocyte-Endothelial Interaction After Deep Hypothermic Preservation.

CONCLUSIONS Hypothermia exerts a protective effect consisting of reduced leukocyte-endothelial interaction. Rewarming after hypothermic preservation, however, causes considerable upregulation of leukocyte infiltration. Downregulation of JAM-A may play a role in modulating TEM during hypothermia and rewarming. We conclude that the rewarming process is an essential but underestimated aspect during transplantation.
PMID: 32080161 [PubMed - in process]

Source: Annals of Transplantation - February 20, 2020 Category: Transplant Surgery Authors: Bogert NV, Werner I, Kornberger A, Vahl CF, Beiras-Fernandez A Tags: Ann Transplant Source Type: research