Hemodialysis removal of caffeine

We read with interest the publication from Kohl et al. “Acute intentional caffeine overdose treated preemptively with hemodialysis” [1]. Caffeine toxicity causes significant adrenergic toxicity that can result in end organ damage and even mortality following massive exposures. Because the structural, physicochemical and pharmacokinetic properties of caffeine are similar to theophylline [2], it is understandable that hemodialysis be considered in caffeine overdose as it would be with theophylline.
Source: The American Journal of Emergency Medicine - Category: Emergency Medicine Authors: Source Type: research